Y177H (p.Tyr177His) variant of STAT2 (P52630)
Y177H (p.Tyr177His) in STAT2 (P52630) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
Y177H (p.Tyr177His) variant details
- p.Tyr177His
- ExAC rs759490169
- TOPMed rs759490169
- gnomAD rs759490169
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- REVEL 0.42
- CADD 23.10
- PolyPhen-2 1.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available