T57I (p.Thr57Ile) variant of STAT2 (P52630)
T57I (p.Thr57Ile) in STAT2 (P52630) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
T57I (p.Thr57Ile) variant details
- p.Thr57Ile
- ExAC rs755128109
- gnomAD rs755128109
- Missense
- Variant Prioritization Score for Impact Estimate 0.118
- REVEL 0.01
- CADD 7.32
- PolyPhen-2 0.16
- SIFT 0.43
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available