T185A (p.Thr185Ala) variant of STAT2 (P52630)
T185A (p.Thr185Ala) in STAT2 (P52630) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
T185A (p.Thr185Ala) variant details
- p.Thr185Ala
- TOPMed rs1242261257
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.09
- CADD 14.90
- PolyPhen-2 0.28
- SIFT 0.20
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available