R32* (p.Arg32Ter) variant of STAT2 (P52630)
R32* (p.Arg32Ter) in STAT2 (P52630) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
R32* (p.Arg32Ter) variant details
- p.Arg32Ter
- rs769566394
- NCI-TCGA Cosmic COSV5847
- cosmic curated COSV58474
- ExAC rs769566394
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.62
- CADD 36.00
- UniProt: Variant assessed as somatic; high impact.
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00038)
- Structural context available