R153K (p.Arg153Lys) variant of STAT2 (P52630)
R153K (p.Arg153Lys) in STAT2 (P52630) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
R153K (p.Arg153Lys) variant details
- p.Arg153Lys
- ExAC rs755691354
- TOPMed rs755691354
- gnomAD rs755691354
- Missense
- Variant Prioritization Score for Impact Estimate 0.078
- REVEL 0.05
- CADD 0.43
- PolyPhen-2 0.00
- SIFT 0.97
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available