L166R (p.Leu166Arg) variant of STAT2 (P52630)
L166R (p.Leu166Arg) in STAT2 (P52630) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
L166R (p.Leu166Arg) variant details
- p.Leu166Arg
- ExAC rs763974330
- gnomAD rs763974330
- Missense
- Variant Prioritization Score for Impact Estimate 0.694
- REVEL 0.81
- CADD 26.00
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available