L159V (p.Leu159Val) variant of STAT2 (P52630)
L159V (p.Leu159Val) in STAT2 (P52630) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
L159V (p.Leu159Val) variant details
- p.Leu159Val
- TOPMed rs1200821507
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.06
- CADD 16.70
- PolyPhen-2 0.55
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 4e-05)
- Structural context available