K178E (p.Lys178Glu) variant of STAT2 (P52630)
K178E (p.Lys178Glu) in STAT2 (P52630) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
K178E (p.Lys178Glu) variant details
- p.Lys178Glu
- ExAC rs766415320
- gnomAD rs766415320
- Missense
- Variant Prioritization Score for Impact Estimate 0.308
- REVEL 0.22
- CADD 20.80
- PolyPhen-2 0.14
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available