K167E (p.Lys167Glu) variant of STAT2 (P52630)
K167E (p.Lys167Glu) in STAT2 (P52630) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
K167E (p.Lys167Glu) variant details
- p.Lys167Glu
- gnomAD rs1278228607
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.05
- CADD 18.90
- PolyPhen-2 0.19
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available