G72S (p.Gly72Ser) variant of STAT2 (P52630)
G72S (p.Gly72Ser) in STAT2 (P52630) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G72S (p.Gly72Ser) variant details
- p.Gly72Ser
- gnomAD rs1318186936
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.03
- CADD 10.30
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available