D26E (p.Asp26Glu) variant of STAG2 (Cohesin subunit SA-2)
D26E (p.Asp26Glu) in STAG2 (Cohesin subunit SA-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
D26E (p.Asp26Glu) variant details
- p.Asp26Glu
- cosmic curated COSV54364
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.12
- CADD 15.90
- PolyPhen-2 0.06
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available