S3T (p.Ser3Thr) variant of SRC (P12931)
S3T (p.Ser3Thr) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, experimental measurements, and structural context.
S3T (p.Ser3Thr) variant details
- p.Ser3Thr
- ExAC rs767602518
- gnomAD rs767602518
- Missense
- Variant Prioritization Score for Impact Estimate 0.42
- REVEL 0.20
- CADD 22.60
- PolyPhen-2 0.01
- SIFT 0.24
- Most common in the South Asian population (allele frequency 0.00013)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.0482