S3I (p.Ser3Ile) variant of SRC (P12931)
S3I (p.Ser3Ile) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S3I (p.Ser3Ile) variant details
- p.Ser3Ile
- gnomAD 20-37384161-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.407
- REVEL 0.21
- MetaLR 0.24
- MetaSVM -0.50
- CADD 24.40
- PolyPhen-2 0.03
- SIFT 0.01
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.0482
- Literature evidence available