S3G (p.Ser3Gly) variant of SRC (P12931)
S3G (p.Ser3Gly) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S3G (p.Ser3Gly) variant details
- p.Ser3Gly
- gnomAD 20-37384160-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.347
- REVEL 0.19
- MetaLR 0.19
- MetaSVM -0.72
- CADD 22.50
- PolyPhen-2 0.00
- SIFT 0.93
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.0482
- Literature evidence available