S17R (p.Ser17Arg) variant of SRC (P12931)
S17R (p.Ser17Arg) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, experimental measurements, and structural context.
S17R (p.Ser17Arg) variant details
- p.Ser17Arg
- Ensembl rs2147049362
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.35
- CADD 25.10
- PolyPhen-2 0.97
- SIFT 0.32
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.353