S17N (p.Ser17Asn) variant of SRC (P12931)
S17N (p.Ser17Asn) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S17N (p.Ser17Asn) variant details
- p.Ser17Asn
- gnomAD 20-37384203-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.493
- REVEL 0.33
- MetaLR 0.43
- MetaSVM -0.35
- CADD 24.90
- PolyPhen-2 0.91
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.353
- Literature evidence available