S17I (p.Ser17Ile) variant of SRC (P12931)
S17I (p.Ser17Ile) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S17I (p.Ser17Ile) variant details
- p.Ser17Ile
- gnomAD 20-37384203-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- REVEL 0.38
- MetaLR 0.46
- MetaSVM -0.18
- CADD 26.40
- PolyPhen-2 0.97
- SIFT 0.00
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.353
- Literature evidence available