S17G (p.Ser17Gly) variant of SRC (P12931)
S17G (p.Ser17Gly) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S17G (p.Ser17Gly) variant details
- p.Ser17Gly
- gnomAD 20-37384202-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.436
- REVEL 0.32
- MetaLR 0.39
- MetaSVM -0.47
- CADD 24.50
- PolyPhen-2 0.91
- SIFT 0.03
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.2e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.353
- Literature evidence available