R16S (p.Arg16Ser) variant of SRC (P12931)
R16S (p.Arg16Ser) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
R16S (p.Arg16Ser) variant details
- p.Arg16Ser
- gnomAD 20-37384199-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.26
- MetaLR 0.25
- MetaSVM -0.76
- CADD 19.90
- PolyPhen-2 0.03
- SIFT 0.03
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.466
- Literature evidence available