R15S (p.Arg15Ser) variant of SRC (P12931)
R15S (p.Arg15Ser) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
R15S (p.Arg15Ser) variant details
- p.Arg15Ser
- gnomAD 20-37384196-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.06
- MetaLR 0.14
- MetaSVM -0.93
- CADD 20.60
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.372
- Literature evidence available