R15L (p.Arg15Leu) variant of SRC (P12931)
R15L (p.Arg15Leu) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
R15L (p.Arg15Leu) variant details
- p.Arg15Leu
- gnomAD 20-37384197-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.333
- REVEL 0.07
- MetaLR 0.25
- MetaSVM -0.60
- CADD 23.10
- PolyPhen-2 0.01
- SIFT 0.04
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.372
- Literature evidence available