Q36R (p.Gln36Arg) variant of SRC (P12931)
Q36R (p.Gln36Arg) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Q36R (p.Gln36Arg) variant details
- p.Gln36Arg
- gnomAD 20-37384260-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.301
- REVEL 0.11
- MetaLR 0.22
- MetaSVM -0.64
- CADD 21.90
- PolyPhen-2 0.05
- SIFT 0.03
- Most common in the East Asian population (allele frequency 2.9e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.112
- Literature evidence available