P8P (p.Pro8Pro) variant of SRC (P12931)
P8P (p.Pro8Pro) in SRC (P12931) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P8P (p.Pro8Pro) variant details
- p.Pro8Pro
- rs1329691407
- gnomAD 20-37384177-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.329
- CADD 14.80
- Most common in the African/African-American population (allele frequency 3.1e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.496
- Literature evidence available