P8H (p.Pro8His) variant of SRC (P12931)
P8H (p.Pro8His) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P8H (p.Pro8His) variant details
- p.Pro8His
- gnomAD 20-37384176-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.511
- REVEL 0.37
- MetaLR 0.37
- MetaSVM -0.34
- CADD 25.90
- PolyPhen-2 0.67
- SIFT 0.01
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.496
- Literature evidence available