P33L (p.Pro33Leu) variant of SRC (P12931)
P33L (p.Pro33Leu) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P33L (p.Pro33Leu) variant details
- p.Pro33Leu
- cosmic curated COSV62439
- 1000Genomes rs2070410421
- TOPMed rs2070410421
- Missense
- Variant Prioritization Score for Impact Estimate 0.398
- REVEL 0.16
- CADD 23.20
- PolyPhen-2 0.02
- SIFT 0.01
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score 0.115