P33A (p.Pro33Ala) variant of SRC (P12931)
P33A (p.Pro33Ala) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P33A (p.Pro33Ala) variant details
- p.Pro33Ala
- TOPMed rs1371352984
- gnomAD rs1371352984
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.12
- CADD 18.60
- PolyPhen-2 0.01
- SIFT 0.08
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available
- SRC SH3 domain domainome 1.0: score 0.115