P20T (p.Pro20Thr) variant of SRC (P12931)
P20T (p.Pro20Thr) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P20T (p.Pro20Thr) variant details
- p.Pro20Thr
- gnomAD 20-37384211-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.11
- MetaLR 0.20
- MetaSVM -0.96
- CADD 19.10
- PolyPhen-2 0.01
- SIFT 0.30
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.3
- Literature evidence available