P20L (p.Pro20Leu) variant of SRC (P12931)
P20L (p.Pro20Leu) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P20L (p.Pro20Leu) variant details
- p.Pro20Leu
- gnomAD 20-37384212-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.11
- MetaLR 0.23
- MetaSVM -0.91
- CADD 20.30
- PolyPhen-2 0.00
- SIFT 0.06
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.3
- Literature evidence available