N4Y (p.Asn4Tyr) variant of SRC (P12931)
N4Y (p.Asn4Tyr) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
N4Y (p.Asn4Tyr) variant details
- p.Asn4Tyr
- gnomAD 20-37384163-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.14
- MetaLR 0.18
- MetaSVM -0.93
- CADD 21.90
- PolyPhen-2 0.01
- SIFT 0.01
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.384
- Literature evidence available