N23T (p.Asn23Thr) variant of SRC (P12931)
N23T (p.Asn23Thr) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, experimental measurements, and structural context.
N23T (p.Asn23Thr) variant details
- p.Asn23Thr
- ExAC rs764712270
- gnomAD rs764712270
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.17
- CADD 8.37
- PolyPhen-2 0.01
- SIFT 0.60
- Most common in the South Asian population (allele frequency 0.0002)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.878