N23K (p.Asn23Lys) variant of SRC (P12931)
N23K (p.Asn23Lys) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
N23K (p.Asn23Lys) variant details
- p.Asn23Lys
- gnomAD 20-37384222-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.10
- MetaLR 0.16
- MetaSVM -0.92
- CADD 5.21
- PolyPhen-2 0.03
- SIFT 0.04
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.878
- Literature evidence available