K7R (p.Lys7Arg) variant of SRC (P12931)
K7R (p.Lys7Arg) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
K7R (p.Lys7Arg) variant details
- p.Lys7Arg
- gnomAD 20-37384173-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.489
- REVEL 0.39
- MetaLR 0.47
- MetaSVM -0.07
- CADD 28.70
- PolyPhen-2 0.95
- SIFT 0.00
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.165
- Literature evidence available