K5N (p.Lys5Asn) variant of SRC (P12931)
K5N (p.Lys5Asn) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, experimental measurements, and structural context.
K5N (p.Lys5Asn) variant details
- p.Lys5Asn
- gnomAD rs1262407930
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.28
- CADD 25.40
- PolyPhen-2 0.98
- SIFT 0.11
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.985