K5E (p.Lys5Glu) variant of SRC (P12931)
K5E (p.Lys5Glu) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
K5E (p.Lys5Glu) variant details
- p.Lys5Glu
- gnomAD 20-37384166-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- REVEL 0.41
- MetaLR 0.46
- MetaSVM -0.13
- CADD 31.00
- PolyPhen-2 0.95
- SIFT 0.00
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.985
- Literature evidence available