H25Q (p.His25Gln) variant of SRC (P12931)
H25Q (p.His25Gln) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
H25Q (p.His25Gln) variant details
- p.His25Gln
- gnomAD 20-37384228-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.22
- MetaLR 0.21
- MetaSVM -0.95
- CADD 0.24
- PolyPhen-2 0.13
- SIFT 0.23
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.632
- Literature evidence available