G2V (p.Gly2Val) variant of SRC (P12931)
G2V (p.Gly2Val) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G2V (p.Gly2Val) variant details
- p.Gly2Val
- gnomAD 20-37384158-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.659
- REVEL 0.62
- MetaLR 0.53
- MetaSVM 0.03
- CADD 29.80
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.196
- Literature evidence available