G29W (p.Gly29Trp) variant of SRC (P12931)
G29W (p.Gly29Trp) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G29W (p.Gly29Trp) variant details
- p.Gly29Trp
- rs367543239
- ClinGen CA226015
- ClinVar RCV000084816
- TOPMed rs367543239
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.27
- CADD 23.30
- PolyPhen-2 1.00
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 3.4e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.19