G28S (p.Gly28Ser) variant of SRC (P12931)
G28S (p.Gly28Ser) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G28S (p.Gly28Ser) variant details
- p.Gly28Ser
- ExAC rs750998052
- gnomAD rs750998052
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.13
- CADD 13.70
- PolyPhen-2 0.01
- SIFT 0.30
- Most common in the East Asian population (allele frequency 8.5e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.128