G28C (p.Gly28Cys) variant of SRC (P12931)
G28C (p.Gly28Cys) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G28C (p.Gly28Cys) variant details
- p.Gly28Cys
- gnomAD 20-37384235-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.30
- MetaLR 0.19
- MetaSVM -0.92
- CADD 19.60
- PolyPhen-2 0.54
- SIFT 0.05
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.128
- Literature evidence available