G26R (p.Gly26Arg) variant of SRC (P12931)
G26R (p.Gly26Arg) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G26R (p.Gly26Arg) variant details
- p.Gly26Arg
- ExAC rs779676153
- TOPMed rs779676153
- gnomAD rs779676153
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.25
- CADD 10.80
- PolyPhen-2 0.30
- SIFT 0.10
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.0804