G26D (p.Gly26Asp) variant of SRC (P12931)
G26D (p.Gly26Asp) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G26D (p.Gly26Asp) variant details
- p.Gly26Asp
- gnomAD 20-37384230-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.26
- MetaLR 0.19
- MetaSVM -0.87
- CADD 12.70
- PolyPhen-2 0.12
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.0804
- Literature evidence available