G26C (p.Gly26Cys) variant of SRC (P12931)
G26C (p.Gly26Cys) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G26C (p.Gly26Cys) variant details
- p.Gly26Cys
- ExAC rs779676153
- TOPMed rs779676153
- gnomAD rs779676153
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.27
- CADD 20.60
- PolyPhen-2 0.77
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.0804