F32S (p.Phe32Ser) variant of SRC (P12931)
F32S (p.Phe32Ser) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, experimental measurements, and structural context.
F32S (p.Phe32Ser) variant details
- p.Phe32Ser
- cosmic curated COSV10969
- ExAC rs754705008
- gnomAD rs754705008
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.24
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 0.42
- Most common in the Middle Eastern population (allele frequency 0.00018)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.158