F32L (p.Phe32Leu) variant of SRC (P12931)
F32L (p.Phe32Leu) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
F32L (p.Phe32Leu) variant details
- p.Phe32Leu
- gnomAD 20-37384247-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.15
- MetaLR 0.14
- MetaSVM -0.89
- CADD 20.90
- PolyPhen-2 0.00
- SIFT 0.23
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.158
- Literature evidence available