E22E (p.Glu22Glu) variant of SRC (P12931)
E22E (p.Glu22Glu) in SRC (P12931) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
E22E (p.Glu22Glu) variant details
- p.Glu22Glu
- rs1182247021
- gnomAD 20-37384219-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.217
- CADD 9.24
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.629
- Literature evidence available