E22D (p.Glu22Asp) variant of SRC (P12931)
E22D (p.Glu22Asp) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
E22D (p.Glu22Asp) variant details
- p.Glu22Asp
- gnomAD 20-37384219-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.209
- REVEL 0.17
- MetaLR 0.15
- MetaSVM -0.91
- CADD 13.90
- PolyPhen-2 0.00
- SIFT 0.61
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.629
- Literature evidence available