E22* (p.Glu22Ter) variant of SRC (P12931)
E22* (p.Glu22Ter) in SRC (P12931) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
E22* (p.Glu22Ter) variant details
- p.Glu22Ter
- gnomAD 20-37384217-G-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.842
- CADD 36.00
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.629
- Literature evidence available