E19K (p.Glu19Lys) variant of SRC (P12931)
E19K (p.Glu19Lys) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
E19K (p.Glu19Lys) variant details
- p.Glu19Lys
- gnomAD 20-37384208-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.398
- REVEL 0.20
- MetaLR 0.23
- MetaSVM -0.72
- CADD 23.70
- PolyPhen-2 0.05
- SIFT 0.00
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.464
- Literature evidence available