E19D (p.Glu19Asp) variant of SRC (P12931)
E19D (p.Glu19Asp) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
E19D (p.Glu19Asp) variant details
- p.Glu19Asp
- gnomAD 20-37384210-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.11
- MetaLR 0.13
- MetaSVM -1.01
- CADD 19.20
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.464
- Literature evidence available