D10Y (p.Asp10Tyr) variant of SRC (P12931)
D10Y (p.Asp10Tyr) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
D10Y (p.Asp10Tyr) variant details
- p.Asp10Tyr
- gnomAD 20-37384181-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- REVEL 0.41
- MetaLR 0.31
- MetaSVM -0.34
- CADD 26.30
- PolyPhen-2 0.44
- SIFT 0.00
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.245
- Literature evidence available